报告题目：Acidic Rhodium(I) Catalyzed Reactions for the Synthesis of Bioactive Natural Products and Privileged Heterocycles

报告人：Weiping Tang教授

 (University of Wisconsin-Madison)

主持人：赵晓丹 教授

时  间：2014年6月24日（星期二）下午16:00

地  点：中山大学丰盛堂芙兰学术中心A403

欢迎广大师生参加！

 

报告人简介:

Education and Training

1992-1997, Peking University, B.S., Chemistry

1997-1999, New York University, M.S., Chemistry

1999-2005, Stanford University, Ph.D., Organic Chemistry

2005-2007, Harvard University, Postdoc, Chemical Biology and Medicinal Chemistry

 

Professional Experience

2007-2013, Assistant Professor, School of Pharmacy, University of Wisconsin-Madison

2013-present, Associate Professor, School of Pharmacy and Department of Chemistry,

University of Wisconsin-Madison

 

Other appointments at the University of Wisconsin-Madison

2007-present Trainer, Chemistry-Biology Interface (CBI) Training Program

2008-present Faculty mentor, Undergraduate Research Scholars Program (URS)

 

Awards and Honors

Boehringer Ingelheim Pharmaceuticals, Inc. Predoctoral Fellowship (2002)

Amgen Predoctoral Fellowship (2003)

Howard Hughes Medical Institute Postdoctoral Fellowship (2005-2007)

Thieme Synlett/Synthesis Journal Award (2010)

 

Selected Publications

1. "Rhodium-Catalyzed Tandem Annulation and (5+1) Cycloaddition: 3-Hydroxy-1,4-enyne as the 5-Carbon Component."
Li, X.; Song, W.; Tang, W.* J. Am. Chem. Soc. 2013, 135, 16797-16800.

 

2. "Transfer of Chirality in the Rhodium-Catalyzed Intramolecular [5+2] Cycloaddition of 3-Acyloxy-1,4-Enynes (ACEs) and Alkynes: Synthesis of Enantioenriched Bicyclo[5.3.0]decatrienes."
Shu, X.-Z.; Schienebeck, C. M.; Song, W.; Guzei, I. A.; Tang, W.* Angew. Chem. Int. Ed. 2013, 52, 13601-13605.
Highlight in Synfacts, 2014, volume 10, issue 3, 0295 (doi:10.1055/s-0033-1340687)


3. "Stereoselective Total Synthesis of Hainanolidol and Harringtonolide via Oxidopyrylium-Based [5+2] Cycloaddition."
Zhang, M.; Liu, N.; Tang, W.* J. Am. Chem. Soc. 2013, 135, 12434-12438.

 

4. "Rh-Catalyzed (5+2) Cycloadditions of 3-Acyloxy-1,4-enynes and Alkynes: Computational Study of Mechanism, Reactivity, and Regioselectivity."
Xu, X.;* Liu, P.; Shu, X.-Z.; Tang, W.*; Houk, K. N.* J. Am. Chem. Soc. 2013, 135, 9271-9274.

 

5. "Generation of Rhodium(I) Carbenes from Ynamides and Their Reactions with Alkynes and Alkenes."
Liu, R.; Winston-McPherson, G. N.; Yang, Z.-Y.; Zhou, X.; Song, W.; Guzei, I. A.; Xu, X.;* Tang, W.* J. Am. Chem. Soc.2013, 135, 8201–8204.

 

6. "Rhodium- and Platinum-catalyzed [4+3] Cycloaddition with Concomitant Indole Annulation: Synthesis of Cyclohepta[b]indoles"
Shu, D.; Song, W.; Li, X.; Tang, W.* Angew. Chem. Int. Ed.2013, 52, 3237-3240.