题  目：Structural insight into regulation of the conformation ofendophilin by Ca2+

主讲人：Dr. Ji-fang Zhang

Associated Professor

Department of Molecular Physiology and Biophysics

Thomas Jefferson University, USA

主持人：陈元教授

中山大学中山医学院神经生物学中心

时   间：2014年11月11日（星期二）下午15:00时

地   点：中山大学北校区永生楼四楼讲学厅

 

主讲人简介：

Dr. Zhang received his Ph.D. in Pharmacology from Columbia University in 1991. His postdoctoral research in the Department of Neuroscience at the Stanford University focused on the function of calcium ion channels. In 1996 Dr. Zhang moved to the University of Pennsylvania as an Assistant Professor in Department of Pharmacology. He joined the school of medicine in Thomas Jefferson University after 2003 as anassociate Professor of the Molecular Physiology and Biophysics department. Dr. Zhang’s lab is interested in voltage-gated Ca2+ channels (VGCCs) and Ca2+ influx in neuronal signaling, in particular, focus on identification and functional characterization of novel Ca2+ channel partner proteins and their roles in Ca2+-dependent signaling in neurons. Recently, hisresearch interests have expanded to using structural approaches to understand how Ca2+ can change the conformations of the Ca2+-binding proteins, such as endophilin and calmodulin. So far, Dr. Zhanghad published many papers inNature, Cell, Neuron, Nat Neuroscience, PNAS, J of Neuroscience, Cell Structure, et al. In 2012, Dr. Zhang was supported as an Overseas Excellent Expertsfrom the State Foreign Experts Bureau. He is also a section member of NIH NTRC.

 

 

 

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